Immune System | GMO SCIENCE https://gmoscience.org A public platform where genetically engineered (GE) crop and food impacts are openly discussed and thoughtfully analyzed. Wed, 29 Nov 2023 23:39:51 +0000 en-US hourly 1 https://wordpress.org/?v=6.4.1 https://gmoscience.org/wp-content/uploads/2023/11/cropped-fav-icon-32x32.png Immune System | GMO SCIENCE https://gmoscience.org 32 32 Guest blog: Glyphosate/AMPA and Asthma in Argentina https://gmoscience.org/2023/11/29/guest-blog-glyphosate-ampa-and-asthma-in-argentina/ Wed, 29 Nov 2023 23:36:42 +0000 https://gmoscience.org/?p=1581 Note from GMOScience: Chuck Benbrook, PhD in agricultural economics, (https://hygeia-analytics.com/about/who-we-are/) writes about the publication of a recent shocking study from Argentina exposing the explosion of asthma in the Argentinian city of Monte Maiz from pesticides (1). 
Glyphosate/AMPA and Asthma in Argentina; reflections on a concerning new study 
This is why glyphosate joins a relatively few pesticides as an essentially unavoidable, ubiquitous global pollutant of the human body and human genome.” Chuck Benbrook, PhD 
 
 
Thisis an important study, with some novel findings. They report much higher levels of GLY and AMPA in the soils/dust inside the small town of Monte Maiz, which is surrounded by ~100,000 hectares of GMO corn+beans, and some wheat. Sources of GLY/AMPA in the city are drift from applications, drifting dust, grain storage facilities, pesticide storage and application equipmentsites, and use in the city. But why higher levels in the city soils, compared to surrounding farm fields? 
 
Might it be faster breakdown in farm fields because of cultivation, increasing levels? The patterns of GLY/AMPA levels across the town suggest blowing dust, the grain handling/storage facility (GLY on husks), and pesticide storage/handling sitesare primary sources. 
 
Reported average rate of GLY per hectare of GE corn+beans =10 kg or almost 9 pounds a.i. per acre. This is about 6.9-times higher than average GLY application rates on soybeans in 2018 in the Heartland USA.(2) Access all GLY application rate and use data in USA via the interactivetables on Hygeia Analytics athttps://hygeia-analytics.com/tools/puds/by-crop/ 
 
Sorting out the impact of GBHs on adverse health outcomes across South America is made more complicated by the fact that heavy GBH use is accompaniedby heavy use of several other high-risk pesticides, e.g., endosulfan, chlorpyrifos, 2,4-D, paraquat, dicamba. Still, based on my knowledge of the literature, there is compelling evidence that GBH use and exposures have emerged, worldwide, as among the most damaging pesticide public health threats ever, despite the indisputably favorable toxicity-to-efficacy ratio for GBHs compared to almost all other herbicides. 
 
it is clear to me that the public health toll triggered bycurrent GBH use patterns and reliance is exposure driven (multiple routes, millions of people receiving high or very high doses daily). High exposures are, in turn, inevitably brought about by use so extensive, for so long, that now soil, water, air, and fire (smoke) are all contaminated to one degree or another,and all move around and come into contact with the human community, essentially everywhere. 
 
This is why GLY joins a relatively few pesticides as an essentially unavoidable, ubiquitous global pollutant of the human body and human genome. 
 
I ask the above questions re levels in the soil in Monte Maiz because the Heartland Study team is tackling the same basic question — where is the GLY coming from that is exposing pregnant women in the Heartland? We have a pretty good sense of dietary exposures (daily, but generally low), and some data to estimate drinking water-related exposures, but we have to figure out a way to quantify likely inhalation exposures and dermal exposures, both to direct sprays and volatilized herbicides, and GLY/AMPA bound to blowing soil and grain dust. 
 

  1. Medardo Avila-Vázquez, Flavia Difilippo, Bryan Mac Lean, et al.Risk of asthma and environmental exposure to glyphosate in an ecological study.Authorea.August 13, 2020.DOI:10.22541/au.159734524.47178780
  2. https://heartlandstudy.org/; The Heartland Study is presently enrolling 2,000 mother-infant pairs living in the Midwest measuring herbicide levels in moms and babies.  Pregnancy outcomes and the health and development of the infants will be tracked for the first three years of life.  Dr. Benbrook is a founding member of the study and Science Advisor.  Dr. Perro, EDGMOScience, is also an Advisory Board Member for the study. 
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The State of our Children’s Health https://gmoscience.org/2023/10/09/the-state-of-our-childrens-health/ https://gmoscience.org/2023/10/09/the-state-of-our-childrens-health/#respond Mon, 09 Oct 2023 23:36:20 +0000 https://gmoscience.org/?p=4759

Rhetoric, regulatory capture, and the lack of governmental action have created and fueled one of the greatest crimes of the times which is the allowance and acceptance of the chronic poisoning of our children.  Although the root causes of this health-crisis-tsunami can be blamed on many factors, the overarching culprit began with the introduction of genetically modified organisms (GMOs) in the 1990s, developed with their associated pesticides.  The usage of a greater variety of GMOs in combination with more toxic pesticides has only been increasing secondary to weed resistance.  Coupled with companies profiteering from the patent-parade of more and more genetically engineered foods, this is the cocktail for the present health disaster played out in real-time. 

The end result is that the state of our children’s health is the true pandemic.

A Look at the Stats

According to a research publication in 2011, 54% of American children were diagnosed with a chronic health condition.  A recent examination of the statistics reveals startling information regarding the status of our children’s health:

  • 1 in 6 to 1 in 8 children have asthma (higher in African American and Latino children
  • 1 in 5 children have eczema, often affecting 60% of infants
  • 2-3 in 6 children have seasonal allergies (many children believe this is typical, with ‘sick being the new normal’)
  • 1 in 3 children have food intolerance and 1 in 12 children have a “true” food allergy
  • 1 in 3-5 children are overweight, variable by state in which they reside
  • Additionally, educators, legislators, and practitioners cannot ignore the elephant in the room: The unprecedented rise of Autism Spectrum Disorder (ASD) in our children.  Many of those affected have now become adults, so the issue has transcended into the population at large.  In the short time between the years from 2020-23 alone, ASD rose significantly and the following numbers should sound the alarm: 1 in 22 children  (CDC, 2023) in California and 1 in 36 children (CDC, 2023) are now on the autism spectrum.  These numbers do not address the millions of children also experiencing ADHD, neurocognitive/neurodevelopmental disorders, mood dysregulation, and anxiety/depression.  Diagnoses are not pigeon-holed, and many children may cross-over manifesting elements of different disorders.  It is a hot mess.

This is an incomplete list of disorders, and nor does it acknowledge the millions of children who are undiagnosed, many lacking resources and support.

Covid Impacts

There is no longer just one elephant in the room, but the herd.  The Covid Era has ushered in layered and more complicated issues upon our children, reflected in a decline their well-being.  Several years of social isolation from peers, masking, closure of schools and childcare centers, reduced access to playgrounds, and overall familial stress have fueled a national mental health crisis.  These changes also were noted in the behavior of children, also documented in their microbiome as well.  (The microbiome is directly responsible for the development of immune function, the first line of defense for detoxification, production of vitamins and neurotransmitters, etc.)  During the early stages of a child’s life particularly in the first 3 years, the gut microbiome has been shown to be shaped by environmental influences.  These changes impact future mental and physical health throughout the child’s life.

Image credit: Sandra Montanez/Getty  

Children and Mental Health

There are definable factors that have changed mental health in children during the Covid Era.  The effects on the microbiome have been mentioned, and this is important in terms of understanding the relationship between the gut and the brain, referred to as the gut-brain axis.  Additionally, the factors that have created the increase in mental health stressors include:

  • Disruption of routines
  • Social disconnection
  • Increased stress in parents and family members
  • Messaging regarding continual dangers and threats to once normal activities
  • Loss and grief of important relationships outside the immediate family

It must be emphasized that children do not have control over their environments, and a year of their lives is extremely significant in the context of their short lives.  Recently released data shows that pandemic-related disruptions and mental health in our youth has produced an increase in anxiety and depression, suicidal ideation, and suicidal attempts compared to before the pandemic, exacerbated in vulnerable populations.

A pivotal study from the UK, the Myriad Project, involved more than 28,000 children, 650 teachers, 100 schools, and 20 million data points.   They published a comparative analysis of the mental health of thousands of UK secondary school pupils presently to those prior to the Covid pandemic.  A summary of their findings is concerning:

  • Young people who went through the pandemic were more likely to experience increased depression, social, emotional and behavioral difficulties and worsening general mental well-being.
  • While mental health declined in both groups over time, those in the pandemic experienced a worsening in their mental health:
    • Cases of depression increased 8.5% in those going through the pandemic versus 0.3% in the pre-pandemic group.
    • Cases of high/very high social, emotional and behavioral difficulties increased 7.9% in the pandemic cohort vs 3.5% in the pre-pandemic cohort.
    • Cases of possible/probable mental health difficulties increased 12.8% in the pandemic group versus 4.5% in the pre-pandemic group.
  • Girls and those who were initially at low risk of mental health difficulties experienced greater deteriorations during the pandemic.
  • Having a positive school climate, good relationships at home and having a friend to turn to for support during lock-down were protective factors.
  • Even partial school attendance during lock-down was better for the subsequent adjustment when coming back to school than no attendance at all.
  • The financial impact of the increase in mental health costs soared 26% higher during the pandemic than previously, led by anxiety and ADHD, recently published in the Journal of the American Medical Association.  Additionally, Telehealth services were used 30 times more often than prior to the pandemic.

Back to School

It is clear that children going back to school is a key factor for the recapture of overall health losses sustained during the Covid pandemic  The message here is that the optimization of the school environment is a essential in regaining children’s well-being, and reversing the disastrous mental health deteriorations experienced.  One of the key ways to regain and strengthen the health of our children is via nutrition.

School nutrition is one of the best ways to support children’s transition back-to-school and back-to-health.

Optimal nutrition in children’s diets can used as a measure of health resilience, (especially during peak viral seasons).  Maximizing nutrition impacts affect every aspect of a child’s health, particularly in regard to learning.  An adequate amount of minerals (i.e., iron, zinc, magnesium), B vitamins, omega 3s, and quality macronutrients in terms of proteins, fats, and carbohydrates, will improve the learning capacity of children.  Many American children receive the bulk of their meals from school lunches.

The National School Lunch Program (NSLP) provides low-cost or free lunches to children, operating in over 100,000 schools/child care facilities.  Many of the increased meals provided during the Pandemic, have since expired in 2022.  Common sense dictates that participation in the USDA’s school lunch program can significantly reduce food scarcity facing many of America’s youth. Children from homes with food insecurity are more likely to eat school meals, receiving the majority of their nutrition from the meals provided.

The question is do the school lunches provide the necessary nutrition to feed children, especially those children who are more vulnerable?  Presently, school meals must meet Federal nutrition standards.  Those dietary guidelines published in the 2020-2025 Executive Summary state the following:

“…Nutritional needs should be met primarily from foods and beverages—specifically, nutrient-dense foods and beverages. Nutrient-dense foods provide vitamins, minerals, and other health-promoting components and have no or little added sugars, saturated fat, and sodium. A healthy dietary pattern consists of nutrient-dense forms of foods and beverages across all food groups, in recommended amounts, and within calorie limits.

The core elements that make up a healthy dietary pattern include:

  • Vegetables of all types—dark green; red and orange; beans, peas, and lentils; starchy; and other vegetables
  • Fruits, especially whole fruit
  • Grains, at least half of which are whole grain
  • Dairy, including fat-free or low-fat milk, yogurt, and cheese, and/or lactose-free versions and fortified soy beverages and yogurt as alternatives
  • Protein foods, including lean meats, poultry, and eggs; seafood; beans, peas, and lentils; and nuts, seeds, and soy products
  • Oils, including vegetable oils and oils in food, such as seafood and nuts”

This is an excellent summary of the nutritional needs of our children and should be commended in the government’s approach to school-based nutrition.

However, is this what our children are actually receiving in school lunches?

Moms Across America National School Lunch Testing Study

The nonprofit organization, Moms Across America (MAA) in Sept. 2022, published their own research regarding what is actually in school meals, disproportionately feeding underserved children.  Forty-three school lunches were sampled from across the US.  The MAA findings are stunning:

  • 95.3% of the school lunch items contained carcinogenic, endocrine disrupting, and liver disease-causing glyphosate, as well as its toxic breakdown product, AMPA.
  • 74% of the samples contained at least one of 29 harmful pesticides.
  • 4 Veterinary drugs and hormones were found in 9 school lunches samples at levels up to 130.76 ng/g.
  • 100% of the school lunch samples contained heavy metals at levels up to 6,293 X higher than the EPA’s maximum levels allowed in drinking water.
  • The majority of the samples were abysmally low in nutrients.

School lunches contain many genetically modified foods, such as corn, soy, canola and soybean oils, and sugar from sugar beets.  GMO foods, designed to resist the spraying of pesticides (Roundup®-ready) are heavily doused with chemicals such as glyphosate-based herbicides. GMOs are engineered to resist dying from spraying from pesticides.  Hence, the weeds die, but not the crops. Many crops (such as wheat, oats, and legumes) are sprayed with an off-label usage of herbicides prior to harvest to dry the crops (applied as a desiccant). Therefore, those foods that our school children commonly consume are even further laden with extremely elevated levels of pesticides.

Additionally, what may not be recognized is that GMOs in themselves cause harm.  The first study of the effects of GMOs in rats showed that GMOs (without concomitant pesticides) caused gastrointestinal disruptions, immune dysfunction, and reproductive harm in rats.  There have been no peer reviewed, blinded studies regarding the harmful effects of GMOs on human health.  Remember, GMOs are not consumed alone, but with their associated pesticides.  Our children are the science experiment.

The introduction of GMOs and their associated pesticides are the main drivers of the chronic poisoning of America’s children.

What harms do glyphosate-based herbicides (including the undeclared toxic “inert” ingredients in formulations), pesticides, heavy metals, and veterinary pharmaceuticals found in American school lunches do to our children?

  • Half of the gut microbes are sensitive to glyphosate, (a patented antibiotic), causing an imbalance in the microbiome with overgrowth of pathogens, leading to disorders such as irritable bowel syndrome and other gut inflammatory conditions.
  • Maternal glyphosate exposure causes ASD in their offspring.
  • Glyphosate is a metal chelator, binding the essential minerals needed for children’s optimal function.
  • Glyphosate is linked to fatty liver disease (NAFLD), affecting 25% of the worldwide population; approximately 13% of children, and 17% of adolescents.  This number rises significantly in children that are overweight.  NAFLD is now the most common form of liver disease in children and can silently lead to more serious steatohepatitis, and ultimately fibrosis.  Extremely low doses of glyphosate have caused NAFLD.
  • Pesticide formulations are contaminated with heavy metals, such as arsenic, chromium, cobalt, lead, and nickel.  Heavy metals cause neurocognitive, respiratory, and cardiovascular disorders, as well as cancer.   The highest levels in school lunches were cadmium at up to 46.8 micrograms/kg and lead up to 94.4 micrograms/kg.
  • Toxic effects of pesticides (glyphosate) on children’s health (i.e., ADHD) has been known and studied in the growing region of the Salinas Valley for 20 years.
  • The “inert” formulations (i.e., POEA) increase the toxicity and are endocrine disruptors:
  • 29 different pesticides were present in 74% of the school lunches.  There are NO studies looking at the toxicity of combinations of pesticide formulations.
  • Veterinary drugs and hormones (anti-fungals, anti-parasitics, and birth control hormones) can have innumerable health effects on children.

Pesticides cause a depletion of vital nutrients.

Robust nutrient levels in foods can offset toxic stressors, however, the depletion of nutrients in the soil have resulted in abysmally low levels in the school lunches tested.  Our children are overfed and undernourished.  Many are constantly hungry since their bodies have not received sufficient nutrition.  Livestock have also not fared well since they, too, are fed contaminated grains which lead to illness.  Children then consume toxic meat.

Solutions

Changing children’s diets to organic regenerative food creates rapid improvements in children’s health, documented in clinical practice as well as in several research studies.

The Nutrinet Sante study looked at 240,000 individuals whose health improved making dietary changes. Local heroes exist.  As documented in What’s Making our Children Sick?, A Central Valley, California family dad living in the heart of pesticide spraying, on the dialysis list, regained kidney function to nearly complete changing from a conventionally grown to an organic regenerative diet.

Our government must do better.  Individual states have taken up some action  on behalf to the protection of children, including California, with the recent passing of    AB 418, banning brominated vegetable oil, potassium bromate, propylparaben, or red dye #3.  Although this type of state-directed legislative action is a good first step, it is not enough in terms of immediate action needed to change the course of health-history and protect our children nationally from the assault by the unregulated ingredients of school lunches.  Legislation is required at the Federal level in order to provide a national standard.  The requirements can look as follows:

  • Support local organic, regenerative farms to supply school lunches, which would also address social equity.  These strategies are presently being addressed in Wisconsin.
  • Support the farm-to-school movement, which is already happening in various states: Pennsylvania, California, Iowa, Minnesota, and Wisconsin.
  • Senator Cory Booker is launching a bill to place restrictions on toxic contamination residues in school lunch, matching European standards.  The only way to achieve those goals is supplying our children with food from regenerative, organic farmers.
  • Support school gardens.  Rodale Institute in Kutztown, PA, has already created and implemented a healthy start school curriculum, My First Garden.
  • Activating local communities raising healthy food consciousness (Las Vegas, Nevada)
  • Support local development, creating neighborhood food networks

The Ask

The expectation is an urgent call-to-action for our policy makers to immediately switch to organic regenerative school lunches for America’s children, reducing pesticides to less that 10 ppb, over the next 3 years.  The stronghold of conventional agricultural practices and businesses on our agricultural practices must be ended.

Our children deserve better.

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You Asked!  We Answered! Do Carbon Filters Eliminate Glyphosate? https://gmoscience.org/2023/01/29/you-asked-we-answered-do-carbon-filters-eliminate-glyphosate/ https://gmoscience.org/2023/01/29/you-asked-we-answered-do-carbon-filters-eliminate-glyphosate/#comments Mon, 30 Jan 2023 00:40:22 +0000 https://gmoscience.org/?p=4075

Reader Kathryn L. asks whether carbon filters can eliminate glyphosate from her drinking water.  Good question!  This is what we found out

As per the EPA, studies show that glyphosate is effectively removed with activated-carbon methods, as well as chlorine and ozone.  There are more than 750 glyphosate-based herbicides on the market, (Roundup being the most renowned), so this is a commonly used and ubiquitous herbicide.

How does glyphosate get into your water, Kathryn?  Run-off and erosion from farms, roadways and public spaces are one of the most common ways it gets into the soil, finding its way into the water supply. It’s water-soluble and in certain conditions can last up to 22 years!  The following map shows how much is being used state-to-state, from 2018:

What makes the issue difficult is that acceptable amounts of glyphosate (there are none!) vary from state-to-state under the Safe Drinking Water Act via the National Primary Drinking Water Regulations.  The EPA established the Maximum Contaminant Level (MCL) of 700 ppb for glyphosate.  Hmm. Researchers found that levels of .1 ppb in rats caused fatty liver disease.  Maybe we should have another look at those levels?

But let’s get back to Kathryn’s question and do a deeper dive into those carbon-based systems.  Carbon-based filters are an effective way to eliminate glyphosate as well as other unwanted chemicals.  The method of action is via the process of adsorption where toxicants bind to the surface of the carbon filter.  To expand the binding capacity of carbon, pores are created that increase the surface area, thus “activating” the carbon in the filter.  The sources of the carbon are from coconut, coal and activated carbon modified through the addition of iron hydroxide.

There are several factors that can affect the binding capacity including the amount of glyphosate present, the pH (ideal is between 4 and 5) and temperature of the water, the type of carbon being utilized as well as how long the water is in contact with the carbon.

The biggest obstacles are cost and the need to change the carbon filter on a regular basis.  While home units might be best, they are definitely higher in price.  Under the sink models and stand-alone pitchers can also do the job!

When do you change the filter?  It depends on the usage, but approximately every 6 months to one year and/or when the carbon filter loses its adsorptive capacity.

Which ones should I buy?  Researching some of the filters out there, some of the leading pitcher-type filters include Clearly Filtered Water, Zero Water, and The Berkey.  This is an incomplete list but will get you thinking about the need to filter your water so that it is clean and affordable.  A drink of pure water to your health, Kathryn, and to all our readers!

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Making our Children Well with Children’s Health Defense TV https://gmoscience.org/2022/11/14/making-our-children-well-with-childrens-health-defense-tv/ Tue, 15 Nov 2022 00:25:13 +0000 https://www.rhi.bio/?p=677630
RHI Advisor, Dr. Michelle Perro, in conversation with Children’s Health Defense TV, featuring Polly Tommey.   Dr. Perro reveals the precipitants causing ill health in our children offering pragmatic, affordable solutions.  A focus on applying the principles of health derived from the kitchen, this is an excellent demonstration between examining the links and benefits of regenerative, organic farming from our food to the family dinner table.

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New Study Reveals: What’s in Our Kids’ School Lunches? https://gmoscience.org/2022/10/26/new-study-reveals-whats-in-our-kids-school-lunches/ https://gmoscience.org/2022/10/26/new-study-reveals-whats-in-our-kids-school-lunches/#comments Wed, 26 Oct 2022 01:21:33 +0000 https://gmoscience.org/?p=3995 GMOScience Team

Oct. 2022

At-A-Glance

  • Moms Across America (MAA) tested American school lunch samples to determine their levels of toxicity and nutrition
  • MAA tested school lunches for glyphosate, pesticides, heavy metals, veterinary hormones, and nutrients and minerals
  • High levels of glyphosate, pesticides, and heavy metals were found in a significant percentage of samples, while veterinary hormones were found in several samples
  • The school lunches were shown to be broadly deficient of nutrients and minerals
  • The high levels of toxicants and low levels of nutrition are linked to a variety of negative health consequences in children, especially impacting low-income children

Every day, millions of American children eat school lunches, yet shockingly little is known about what’s in them. The national coalition Mom’s Across America (MAA) has taken matters into their own hands, conducting tests on children’s school lunches that the federal government has failed to do. They tested 43 school lunch samples from across the country, divided into five main categories:

  • Glyphosate
  • Pesticides
  • Heavy metals
  • Veterinary hormones
  • Nutrients and minerals

Here are the results MAA found:

Glyphosate

Glyphosate is a commercially popular weed killer that has been shown to cause cancer, endocrine disruption, and liver disease. The MAA study revealed a staggering 95.3% of the samples tested had detectable glyphosate levels. It was especially prevalent in wheat products,100% of which tested positive for glyphosate.

Pesticides

Of the 220 most harmful pesticides tested, 74% of school lunch samples contained at least one of them. Two notable pesticides were found in high levels:

  • Thiabendazole (TBZ), an immunosuppressant, was found in 27.9% of samples, especially fruit, such as red and green apples.
  • Piperonal Butoxide (PBO), which causes birth defects and brain dysfunction, was found in 41% of samples. Its highest levels were found in a hamburger.

Heavy Metals

Heavy metals, such as arsenic, cadmium, lead, and mercury, cause significant harm to children’s brain development. They are also linked to problems with the kidneys, respiratory system, cardiovascular system, and cancer. Heavy metals were found in 100% of school lunch samples, with cadmium and lead present at the highest concentrations. Lead levels of .015 µg/kg can cause developmental delays in children; the highest level found in a lunch sample was 94.4 µg/kg.

Veterinary Hormones

Veterinary hormones, often given to livestock and present in meat, are linked to reproductive issues, early onset puberty, cancer, and heart problems. MAA found 4 different veterinary hormones present in 9 school lunch samples.

Nutrients and Minerals

In addition to harmful toxins, MAA also tested for various beneficial nutrients and minerals. They found the school lunches to be deficient in almost every category, most significantly copper, calcium, potassium, and phosphorus. Around 50% of samples lacked sufficient magnesium, zinc, and manganese. All of these minerals are vital to proper body function.

Nutrition is essential to our children’s physical, mental, and developmental health. The MAA study has revealed not only low nutrition in school lunches, but a host of actively harmful toxicants with myriad negative health consequences. This particularly impacts low-income children, for many of whom school lunch may be the only meal they eat that day.

Call to Action

School lunches must not only eliminate this unacceptable toxic load, but make meals more nutritious and healthy for our children at a national level. Our legislators paired with educators must make this action a top priority, on par with other countries globally.  What’s in our children’s school lunches is tied to What’s Making our Children Sick

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